Palliative treatment of bone metastases: analysis of biological effects of MR guided Focused Ultrasound (MRgFUS) versus External Beam Radiation Therapy (EBRT). A randomized comparative trial using Functional Diffusion Maps as molecular activity indicator

نویسندگان

  • Michele Anzidei
  • Alessandro Napoli
  • Giulia Brachetti
  • Maurizio Del Monte
  • Daniel De Olivera
  • Fabrizio Andrani
  • Carola Palla
  • Luca Bertaccini
  • Daniela Musio
  • Vincenzo Tombolini
  • Carlo Catalano
چکیده

Palliative treatment of bone metastases: analysis of biological effects of MR guided Focused Ultrasound (MRgFUS) versus External Beam Radiation Therapy (EBRT). A randomized comparative trial using Functional Diffusion Maps as molecular activity indicator Michele Anzidei, Alessandro Napoli, Giulia Brachetti, Maurizio Del Monte, Daniel De Olivera, Fabrizio Andrani, Carola Palla, Luca Bertaccini, Daniela Musio, Vincenzo Tombolini, Carlo Catalano

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Evaluation safety and efficacy of MRgFUS for palliative treatment of bone metastasis

Background The ExAblate system is a non-invasive thermal ablation device that has been used for the ablation of tissue. This system combines a focused ultrasound surgery delivery system and a conventional diagnostic 1.5 T MRI scanner (MRgFUS/MR guided focused ultrasound surgery). Starting from 2009 up to 2012 our Institute participated in the clinical randomized multi-site study to evaluate saf...

متن کامل

MR-guided focused ultrasound for painful bone metastases: safety when combined with chemotherapy

Background/introduction Magnetic Resonance guided Focused Ultrasound (MRgFUS) is a non-invasive, non-ionizing treatment producing thermal ablation using high intensity focused ultrasound and MR thermometry to denervate pain from bone metastases. A recent phase III study comparing MRgFUS to sham treatment for a painful bone metastasis allowed patients to be treated with concurrent chemotherapy a...

متن کامل

Radiation-induced toxicity after image-guided and intensity-modulated radiotherapy versus external beam radiotherapy for patients with spinal bone metastases (IRON-1): a study protocol for a randomized controlled pilot trial

BACKGROUND Radiation therapy (RT) of bone metastases provides an important treatment approach in palliative care treatment concepts. As a consequence of treatment, the extent of radiation-induced toxicity is a crucial feature with consequences to a patient's quality of life. In this context this study aims at reducing the extent of radiation-induced side effects and toxicity by assuming a bette...

متن کامل

Diagnostic imaging and image-guided therapy of skeletal metastases.

BACKGROUND The high incidence of skeletal metastases in cancer patients warrants careful detection with imaging and follow-up. Efforts are needed to manage pain associated with skeletal metastases as part of overall patient management. METHODS This article reviews the current methods of diagnostic imaging in the evaluation of skeletal metastases and image-guided treatment of bone metastases f...

متن کامل

Single fraction radiotherapy versus multiple fraction radiotherapy for bone metastases in prostate cancer patients: comparative effectiveness

External beam radiotherapy (EBRT) is an effective treatment for symptomatic bone metastases from a variety of primary malignancies. Previous meta-analyses and systematic reviews have reported on the efficacy of EBRT on bone metastases from multiple primaries. This review is focused on the comparative effectiveness of single fraction radiotherapy versus multiple fraction radiotherapy for bone me...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 2  شماره 

صفحات  -

تاریخ انتشار 2014